Custom Proteins
& Reagents

Custom proteins and reagents that improve your assay, manufactured to your specifications

Choose candidates from our wide portfolio of recombinant proteins and enzymes, or bring your own protein, and we will modify it to improve the performance of your assay. Unlike other development companies though, we can also quickly manufacture custom proteins at scale under GMP processes, delivering a consistent and documented product.

Our services develop your proprietary custom proteins and can also enhance existing assays.

  • Large enzyme portfolio

    Get access to a broad portfolio of high-quality enzymes, spanning trusted DNA polymerases, advanced NGS library prep tools, and unique innovations like our NanoStart™ enzyme technology.

    • 85+ proteins/enzymes
    • High concentrations
    • Small and large batch sizes
    • Range of modifications
    • Proven track record
  • Customization options

    We work closely with you to develop the best format and formulations for your chosen application, whether you select from our portfolio or bring your own designed enzyme.

    • Your proteins or ours
    • Functional analysis
    • Wide purification options
    • Bacterial expression
    • Post-translational modifications
  • Stabilization with lyophilization

    Extend the stability and usability of your proteins with our lyophilization expertise. Offering flexible formats from beads to cakes, configured to fit your product and workflow needs.

    • Rapid prototyping
    • Cost effective
    • Beads 1.5-5.0 mm in diameter
    • Unit dose or bulk
    • Cakes and surface coating

Improve assay sensitivity, stability & reliability

Level-up your assay

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Applications We Support

Diagnostics

From optimized storage buffers to modified and custom proteins, we can enhance your assay. With manufacturing under ISO 13485, reagents are ready  for your quality processes. All reagents are Made in USA and BIOSECURE compliant. 

Life Sciences

Our reagents can be found in applications for NGS, lateral flow, flow cytometry, ELISA. PCR, qPCR, ddPCR and more. Organizations trust Fortis to deliver their critical products on-time and to their specifications. 

Custom proteins & formulations

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Support Services Offered

  • Reagent and component procurement
  • Buffer formulations
  • QC testing including functional analysis
  • COA or other documentation
  • Packaging
  • Warehousing
  • Shipping and logistics

Quality

  • ISO 13485 certified since 2009
  • cGMP compliant
  • Full QMS
  • Supplier qualification and monitoring
  • Strong ISO 13485 audit outcomes across multiple certification cycles

Our Latest Custom Protein & Reagents Insights:

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Large enzyme portfolio

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Enzyme Capabilites - Molecular Biology Applications

  • PCR and RT-PCR

    • Taq Polymerase
    • AbTaq Polymerase (Antibody Hot-Start)
    • Flashtaq Polymerase Chemical Hot-Start, Fast Activation)
    • Fastaq Polymerase (Chemical Hot-Start)
    • Pfu High Fidelity Polymerase Variants
    • Sequenase Polymerase
    • KOD High Fidelity Polymerase
    • RTScript Reverse Transcriptase
    • RNase Inhibitors
    • E. coli UNG
    • Cod UNG
    Learn more
  • Next-Generation Sequencing

    • Enzymatic Fragmentation Mix
    • T4 DNA Ligase
    • T4 DNA Polymerase
    • T4G32P SSB Protein
    • E. coli UNG
    • Klenow exo-DNA Polymerase
    • DNA Polymerase I
    • TS2126 Ligase
    • Phi29 Polymerase
    • Phi29 Variant Polymerase
    Learn more
  • Cas Nucleases

    • Cas9
    • LbCas12a
    • LwCas13
    • LbuCas13a
    Learn more
  • Isothermal Amplification

    • Bst Polymerase (+/- NanoStart)
    • Gsp Polymerase (+/- NanoStart™)
    • IsoRT Reverse Transcriptase
    • Thermostable RNase Inhibitor
    • Phi29 Polymerase
    • Phi29 Variant Polymerase
    • TS2126 Ligase
    • T4G32P SSB Protein
    • T4 UvsX Recombinase
    • T4 UvsY
    • Bsu 2.0 DNA Polymerase
    Learn more
  • Other Nucleic Acid Modifying Enzymes

    • TAPP
    • E.coli Alkaline Phosphatase
    • Thermolabile Alkaline Phosphatase
    • Salt Tolerant Nuclease
    • RNaseH
    • Thermostable RNaseH2
    • Exonuclease
    • T7 Exonuclease
    • T7 RNA Polymerase
    • T7 RNA and DNA polymerase
    • λ Exonuclease
    • Biotin ligase
      Proteinase K
    Learn more

Frequently Asked Questions (FAQs)

Yes, all reagents are made in the United States.

Yes, we have extensive experience in tailoring enzymes for use in lyophilized format. This includes glycerol-free lyophilization-compatible enzymes as well as fully formulated lyophilization-ready enzymes or master mixes. In addition with our in-house lyophilization capabilities, we can provide the fully lyophilized solution as well. We can start with your enzyme or use one of our pre-optimized enzymes as the foundation. 

We are able to perform a variety of modifications including alkylation, phosphorylation, adenylation, biotinylation (random and site-specific), and various forms of reversible hot-start modifications. We can also formulate enzymes in buffers that are specific to your platform. 

Either is fine! We have a broad selection of molecular biology enzymes and recombinant proteins that you can choose to customize to fit your needs. If you need a specific peptide sequence manufactured for your use, we are happy to help meet that need as well.

Scale can be rapidly adjusted using our proprietary expression vectors and various cell culture platforms. For most recombinant enzymes, we can provide single lots on the order of micrograms up gram scale.

Most of our off the shelf catalog reagents are labeled for Research Use Only, though our ISO-13485 Certified and cGMP compliant Quality Management System is built to support reagents and raw materials suitable for use in IVD applications. Regardless of the labeled “grade” all of our products are made under our QMS and the specifications can be customized as needed by customers.